Understanding global changes of the mouse brain proteome after vaginal infection with HSV-2 using a label-free shotgun approach

Herpes simplex virus type 2 (HSV-2) is a common human pathogen that establishes lifelong latency in neurons of the nervous system.The number of severe central nervous system infections caused by the virus has increased recently.However, the pathogenesis of HSV-2 infection in the nervous system is not fully understood.Here, we demonstrated global pr

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Conspiracy beliefs and negative attitudes towards outgroups in times of crises: Experimental evidence from Germany.

While research on the determinants of conspiracy beliefs has been growing, there is still limited attention given to e. cuarenta cerveza the broader consequences of conspiracy theories.This study examines the effects of conspiratorial framing on outgroup evaluations in the context of societal crises.Using an experimental design and a large represen

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Exploring the progression of drug dependence in a methamphetamine self-administration rat model through targeted and non-targeted metabolomics analyses

Abstract Persistent neurochemical and biological disturbances resulting from repeated cycles of drug reward, withdrawal, and relapse contribute to drug dependence.Methamphetamine (MA) is a psychostimulant with substantial abuse potential and neurotoxic effects, primarily affecting monoamine neurotransmitter systems in the brain.In this study, we ai

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